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Cas 96829-58-2 Pharmaceutical Raw Materials Orlistat Bulk Powder For Weight Loss

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Cas 96829-58-2 Pharmaceutical Raw Materials Orlistat Bulk Powder For Weight Loss

China Cas 96829-58-2 Pharmaceutical Raw Materials Orlistat Bulk Powder For Weight Loss supplier
Cas 96829-58-2 Pharmaceutical Raw Materials Orlistat Bulk Powder For Weight Loss supplier

Large Image :  Cas 96829-58-2 Pharmaceutical Raw Materials Orlistat Bulk Powder For Weight Loss

Product Details:

Place of Origin: CHINA
Brand Name: MOBELBIO
Certification: ISO

Payment & Shipping Terms:

Minimum Order Quantity: 1 KGS
Price: 1
Packaging Details: Bag
Delivery Time: Within 1-3 Day
Supply Ability: 500Kgs/Month
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Detailed Product Description
Purity: 99% Stahdard: USP/BP

 
Cas 96829-58-2 Pharmaceutical Raw Materials Orlistat Bulk Powder For Weight Loss
 
1.Product Description
 

Orlistat (CAS NO.96829-58-2) is a drug designed to treat obesity. It is mainly used for preventing the absorption of fats from the human diet, thereby reducing caloric intake. Besides, it is intended for use in conjunction with a physician-supervised reduced-calorie diet.

 

2 Specifications:

 

Molecular Formula: C29H53NO5
Molecular Weight: 495.73
CAS NO: 96829-58-2
H bond acceptors: 6
H bond donors: 1
Freely Rotating Bonds: 23
Polar Surface Area: 72.91 Å2
Index of Refraction: 1.469
Molar Refractivity: 141.57 cm3
Molar Volume: 507.5 cm3
Surface Tension: 35.6 dyne/cm
Density: 0.976 g/cm3
Flash Point: 326.3 °C
Melting Point: <50 °C
Enthalpy of Vaporization: 91.36 kJ/mol
Boiling Point: 615.9 °C at 760 mmHg
Vapour Pressure: 4.23E-15 mmHg at 25°C
Storage temp: 2-8°C
Solubility: DMSO: 19 mg/mL
Appearance: Off-White Solid

 

3. Analysis of the standard for 99%

 

Item Requirements Test Results
Appearance while to off-while powder White powder
Identification HPLC retention time Conforms
Melting Point 42 ºC -45°C 42°C-44°C
Specific optical rotation -31.0°~-41.0° -36.0°
Purity by HPLC no less than 98.0% 98.5%
Total impurity no more than 2.0% 1.6%
Max Individual impurity no more than 0.5% 0.3%
Water content%(K&F) no more than 0.5% 0.1%
Residual solvents EtOH no more than 0.5% N.D
EtAC no more than 0.5% N.D
n-Heptane no more than 0.5% less than 0.1%
Residue on ignition less than 0.2% 0.10%
Heavy metals as Pb no more than 20ppm less than20ppm
Assay (HPLC) no less than 98.0% 98.60%
Conclusion Meets the Requirements

 

4. Applications:


Orlistat is used for the treatment of obesity.The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body mass.After orlistat was stopped, a significant number of subjects regained weight—up to 35% of the weight they had lost.

The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).

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