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Nootropics J147 Nootropic Powder J -147 CAS 1146963-51-0 Treatment Of AD

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Nootropics J147 Nootropic Powder J -147 CAS 1146963-51-0 Treatment Of AD

China Nootropics J147 Nootropic Powder J -147 CAS 1146963-51-0 Treatment Of AD supplier
Nootropics J147 Nootropic Powder J -147 CAS 1146963-51-0 Treatment Of AD supplier Nootropics J147 Nootropic Powder J -147 CAS 1146963-51-0 Treatment Of AD supplier

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Product Details:

Place of Origin: China
Brand Name: MOBELBIO
Certification: ISO,SGS

Payment & Shipping Terms:

Minimum Order Quantity: 100 Grams
Price: 1
Packaging Details: Foil Bag
Delivery Time: Within 1-3 Days
Payment Terms: T/T
Supply Ability: 200Kgs/Month
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Detailed Product Description

 

Nootropic J147 J-147 J 147 CAS 1146963-51-0

 

Product Description:

 

API J-147 High purity Neurotrophic molecule cas 1146963-51-0 J147

 

Chemical Formula:   C18H17F3N2O2
CAS #:   1146963-51-0
Molecular Weight:   350.33
Purity:   >99%
Appearance:   white powder
Chemical Name:   (E)-N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N'-(3-methoxybenzylidene)acetohydrazide
Solubility:   Up to 50 mM in DMSO

 

 

J147 was discovered based upon efficacy in multiple cell culture models of age-associated pathologies rather than exclusively amyloid metabolism. It is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer’s disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques, etc. These pleiotrophic effects of a single molecule suggest that J147 has potential for the treatment of AD.

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