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Anti Oxidation Powder Pharmaceutical Raw Materials 7,8- Dihydroxyflavone 38183-03-8 7, 8- DHF

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Good quality Peptide APIs for sales
Good quality Peptide APIs for sales
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Anti Oxidation Powder Pharmaceutical Raw Materials 7,8- Dihydroxyflavone 38183-03-8 7, 8- DHF

Detailed Product Description

 

Anti-oxidation powder 7,8 Dihydroxyflavone CAS 38183-03-8 ( 7, 8-DHF )

 

 

Poduct Name
7,8 Dihydroxyflavone
Synonyms
7,8-dihydroxy-2-phenyl-4h-chromen-4-one
CAS No.
38183-03-8
Appearance
Yellow Powder
Purity(HPLC)
≥99%
MW
254.24
Storage
Store in a well-closed place with constant low temperatureand no direct sun light.

 

7,8-Dihydroxyflavone (7,8-DHF)

is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves.It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).7,8-DHF is both orallybioavailable and able to penetrate the blood–brain barrier.[A prodrug of 7,8-DHF with greatly improved potency andpharmacokinetics, R13 (and, formerly, R7), is under development for the treatment of Alzheimer's disease.

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