Sodium alginate,also called as Algin, is a kind of white or light yellow granular or powder, almost odorless and tasteless. It is a macromolecular compound with high viscosity, and a typical hydrophilic colloids. Because of its properties of stability, thickening and emulsifying, hydratability and gelling property, it is widely used in food, pharmaceutical, printing and dyeing, etc.
In medicine field, because of its unique physical and chemical properties and good biological compatibility, sodium alginate has been widely used as pharmaceutical preparation, tissue engineering, clinical treatment, cell culture, food processing and other fields. In medicine preparation field, sodium alginate is used as thickening agent, suspending agent and disintegrating agent ,it can also be used as microencapsulated material and the cold resistant agents of cells. In addition, it has the functions of reducing blood sugar, antioxidant, enhancing immune activity effect etc.
In recent years, with the development of biomedical materials and exploitation of new drugs, as a kind of high efficient biological adhesion agent and pH sensitivity gel material, sodium alginate has been researched increasingly. With polyelectrolyte properties, sodium alginate is used to make preparation of sustained release microcapsules or pellets. With the gel properties ,it is used to make preparation of gel matrix tablets, With its pH sensitivity ,it is used as a targeted intestinal absorption tablet disintegrate.
In addition, the sodium alginate can also be used as a topical ointment thickener.With sodium alginate in oral tablet, it can increase the viscosity of tablet, thus making gel barrier effect, prolonging drug release time, reducing the adverse reaction. At home, we have made long-term Cedocard Retard tablet with sodium alginate as matrix, and added in antibiotics, hormones, insulin solutions, sodium alginate can produce long lasting effect.
In sodium alginate molecules, there are free carboxyl and hydroxyl groups, which can form gel with a variety of metal ions, and the preparation of pellets are of pH sensitivity, with suitable particle size. It can prevent the sudden release of oral, and it is non-toxic. Sodium alginate gel has a strong biological adhesion. It can be used as local wound healing dressings, preparation of nasal and ocular drug, oral pellicles and chewing tablet. With blood compatibility and vivo degradation removal characteristics, sodium alginate is a good carrier material for drug targeting.
national standards GB1976–2008, Based on customers’ requirements, products in line with E401, FCC III version can also be produced.
|Color and characteristics||Milk white to light yellow or light brown powder or granular|
|Ash (on dry basis) / %||18～27|
25kg poly woven bag
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