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17 Methyltestosterone Testosterone Anabolic Steroid 58 18 4

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number 58-18-4
Minimum Order Quantity 10g
Price US $1-$4
Packaging Details 10g,50g,1kg bag
Delivery Time 1-3 working days to ship, then about 5-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Payment Method
Supply Ability 1000 kg per month
Product Details
Product Names Methyltestosterone Color White
Grade Standard Chemical Grade Purity 99%
Cas No. 58-18-4 Shelf Life 2 Years
MF C20H30O2 Assay HPLC 99%
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17 Methyltestosterone Testosterone Anabolic Steroid

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58 18 4 Testosterone Anabolic Steroid

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17 alpha methyltestosterone

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Product Description

Buy Testosterone Anabolic Steroid Powder 17-Methyltestosterone 58-18-4 For Muscle Growth

17 Methyltestosterone Testosterone Anabolic Steroid 58 18 4 0

Quick Details:

Product name:17-Methyltestosterone 
CAS No:58-18-4
Molecular formula:C20H30O2
Molecular weight:302.46
Appearance:white or off-white crystalline powder
Assay:99%min
Usage:Methyltestosterone is one of the oldest available oral steroids, whick can treat lack of testosterone in men, and treats breast cancer in postmenopausal women. For athletic purposes, methyltestosterone is generally only used to stimulate aggression among power lifters and those looking to boost up their workouts.
 
 
17-Methyltestosterone Description:
17-Methyltestosterone is one of the oldest available oral steroids. It is produced by many various manufacturers and sold in a number of countries including the U.S.. It is quite androgenic, with minimal anabolic effects. For athletic purposes, methyltestosterone is generally only used to stimulate aggression among power lifters and those looking to boost up their workouts.
Many 17-methyltestosterone tablets are sublingual (to be placed under the tongue) for faster absorption. These tabs can generally be identified by a notable citrus flavor to them. A couple tabs placed under the tongue before a visit to the gym may make for an aggressive workout. Aside from this, methyltestosterone offers little except androgenic side effects. It is quite toxic, elevating liver enzymes and causing acne, gynecomastia, aggression and water retention quite easily. Were one to tolerate these side-effects, methyltestosterone will offer little more than some slight strength gains.
 
17-Methyltestosterone Applications:

17alpha-methyl testosterone is used widely as a component of hormone replacement therapy. Previous reports have indicated that contrary to , 17alpha-methyl testosterone is not aromatized. However, 17alpha-methyl testosterone still could affect local estrogen formation by regulating aromatase expression or by inhibiting aromatase action. Both possibilities have important clinical implications.

 

To evaluate the effect of 17alpha-methyl testosterone on the expression and activity of aromatase, we tested the choriocarcinoma Jar cell line, a cell line that express high levels of P450 aromatase, and the macrophage-like THP-1 cells, which express aromatase only after undergoing differentiation. We found that in both cell lines, 17alpha-methyl testosterone inhibits aromatase activity in a dose-related manner. The curve of inhibition parallels that of letrozole and gives complete inhibition at 10(-4) M 17alpha-methyl testosterone, determined by the tritium release assay. 17alpha-methyl testosterone does not have detectable effects on aromatase RNA and protein expression by Jar cells.

 

Undifferentiated THP-1 cells had no aromatase activity and showed no effect of 17alpha-methyl testosterone, but differentiated THP-1 (macrophage-like) cells had a similar inhibition of aromatase activity by 17alpha-methyl testosterone to that seen in Jar cells. The Lineweaver-Burke plot shows 17alpha-methyl testosterone to be a competitive aromatase inhibitor. Our results show for the first time that 17alpha-methyl testosterone acts as an aromatase inhibitor.

 

These findings are relevant for understanding the effects of 17alpha-methyl testosterone as a component of hormone replacement therapy. 17alpha-methyl testosterone may, as a functional androgen and orally active steroidal inhibitor of endogenous estrogen production, also offer special possibilities for the prevention/treatment of hormone-sensitive cancers.

 

 

 

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