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82640 04 8 Raloxifene Hydrochloride Powder For Anti Estrogen

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number 82640-04-8
Minimum Order Quantity 10g
Price negotiable
Packaging Details 10g,50g,1kg bag
Delivery Time 1-3 working days to ship, then about 5-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Payment Method
Supply Ability 1000 kg per month
Product Details
Purity 99% Min Grade Standard Medical Grade
Other Names Raloxifene HCL Cas No. 82640-04-8
Shelf Life 2 Years MF C28H28ClNO4S
Assay HPLC 99% Color White To Pale Yellow Powder
Type Auxiliaries And Other Medicinal Chemicals Einecs No. N/M
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82640 04 8 Raloxifene Hydrochloride Powder

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Anti Estrogen Raloxifene Hydrochloride Powder

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82640 04 8 Raloxifene HCL Powder

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Product Description

Raloxifene Hydrochloride powder CAS 82640-04-8 Raloxifene HCL for Anti Estrogen

 

82640 04 8 Raloxifene Hydrochloride Powder For Anti Estrogen 0

Product name: Raloxifene Hydrochloride

CAS No: 82640-04-8

MF: C28H28ClNO4S

MW: 510.04

Purity: 99%min.

Appearance: Faint yellow powder

Usage : Raloxifene is a selective estrogen receptor modulator (SERM); acts as an anti-estrogen in both breast and uterine tissue while being estrogenic in bone. May have efficacy against estrogen-sensitive cancers.

Description:

Raloxifene (marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.

Evista (Raloxifene Hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of Raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (Agonism) and and the blockade of estrogenic pathways in other tissues (Antagonism).

82640 04 8 Raloxifene Hydrochloride Powder For Anti Estrogen 1

Application:

Raloxifene is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.

Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.

Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.

May prevent or treat corticosteroid-induced bone loss. American College of Rheumatology states that raloxifene can be offered to selected postmenopausal corticosteroid-treated women who refuse hormone replacement therapy or other antiresorptive agents or in whom such therapies are contraindicated.

Reduction in the incidence of invasive breast cancer inpostmenopausal women at high risk for developing the disease. Effect comparable to that of tamoxifen in reducing the risk of invasive breast cancer (STAR trial). No effect on the risk of lobular carcinoma in situ or ductal carcinoma in situ (STAR trial).

Effect on breast cancer incidence in women with BRCA1 or BRCA2 genetic mutations not established. Not indicated for the treatment of breast cancer or to reduce the risk of recurrence of breast cancer. 1 Not indicated for reduction in the risk of noninvasive breast cancer.

 

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