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Contact Person : Wendy WS: +86-13798562250
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99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number 82640-04-8
Minimum Order Quantity 10g
Price negotiable
Packaging Details 10g,50g,1kg bag
Delivery Time 1-3 working days to ship, then about 5-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Payment Method
Supply Ability 1000 kg per month
Product Details
Name Raloxifene Hydrochloride Pacakge Foil Bag;drum
Function Anti- Breast Cancer Appearance Light Yellow Powder
Cas No. 82640-04-8 Shelf Life 2 Years
MF C28H28ClNO4S Assay HPLC 99%
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Product Description

Raloxifene Hydrochloride powder CAS 82640-04-8 Raloxifene HCL for Anti Estrogen

 

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 0

Product name: Raloxifene hydrochloride
Synonyms: Keoxifene
Purity: 99%
CAS No.:82640-04-8
M.F.: C28H29NO4S
M.W.: 475.5992
Appearance: light yellow crystalline powder,
USES: Raloxifene will be like tamoxifen as effective,
and less adverse effects.


Usage:


1. Amino acid, nutrient
2. Labeled Raloxifene, intended for use as an internal standard for the quantification by GC- or LC-mass
spectrometry.
3. A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.


Description:


Raloxifene hydrochloride is a second-generation Selective Estrogen Receptor Modulator (SERM) of the benzothiophene family. This drug is similar in effect to tamoxifen, exhibiting estrogen receptor antagonist (blocking) properties in some tissues while acting as an estrogen receptor agonist (activator) in others.

The main point of variation between these two agents is their tissue selectivity. While raloxifene hydrochloride is a strong anti-estrogen in breast and uterine tissues, it appears to be estrogenic in bone. This allows it to protect bone density, mimicking the beneficial effects of endogenous estradiol. This is quite different from tamoxifen, which is anti-estrogenic in both breast and bone.

In a role that was novel for an anti-estrogen, raloxifene hydrochloride was approved by the FDA for the prevention and treatment of osteoporosis in post-menopausal women. It is also being investigated for several other potential uses, including the treatment and prevention of cardiovascular disease, breast cancer, gynecomastia, prostate cancer, acromegaly, and uterine cancer.

Raloxifene hydrochloride Mechanism of Action:
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors.

This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism). The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors.

Raloxifene appears to act as an estrogen agonist in bone. It decreases bone resorption and bone turnover, increases bone mineral density and decreases fracture incidence.

 

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 1

 

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Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com
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1. We offer RESHIP service with free cost if goods were catched by custom.

 

2.Full experience of large numbers containers loading in Chinese sea port.


3. We provide more customized services:Products, Labels, Boxes.....


4. payment term:,, Bank Transfer and BTC or Another Payment Method.

Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa

 

Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com

 

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 4

 

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Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 5

Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 6

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 7

99% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 499% Purity Raloxifene Hydrochloride Pharmaceutical Raw Materials 82640-04-8 9

Contact US

Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com
 
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