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99% Purity with Competitive Price Injectable Melanotan I CAS 75921-69-6 for Bodybuilding and Skin Color Change

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number 75921-69-6
Minimum Order Quantity 1 box
Price US $40-$80
Packaging Details White box, Carton packaging Or custom packaging.
Delivery Time 1-3 working days to ship, then about 5-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Payment Method
Supply Ability 5000 boxes per month
Product Details
Other Names Melanotan-I Purity 99% Min
Grade Standard Medical Grade Cas No. 75921-69-6
Shelf Life 2 Years MF C78H111N21O19
Assay HPLC 99% Color White Freeze-dried Powder
High Light

HPLC 99 Weight Loss Peptides

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5000iu/ Vial Human Growth Hormone Supplement

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Product Description

99% Purity with Competitive Price Injectable Melanotan I CAS 75921-69-6 for Bodybuilding and Skin Color Change

 

99% Purity with Competitive Price Injectable Melanotan I CAS 75921-69-6 for Bodybuilding and Skin Color Change 0

Quick Information

Product Name Melanotan I
CAS 75921-69-6
Purity 99%
MF C78H111N21O19
MW 1646.85
Payment Method , , Bank Transfer, Bitcoin, Litecoin

 

 

 

Introduction


Melanotan I is a cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (a-MSH) that tends to induce skin tanning. Melanotan II has the additional effect of increasing libido.

 

Researchers there knew that one of the best defenses against skin cancer was a natural tan which has been slowly developed over weeks. They hypothesized that an effective way to reduce skin cancer rates in people would be to induce the body's natural tanning system to produce a protective tan prior to UV exposure. They knew the body's naturally occurring hormone alpha-melanocyte stimulating hormone (α-MSH) caused melanogenesis, a process by which the skin's tanning cells (melanocytes) produce the skin's tanning pigment (melanin). With that knowledge they tested to see if administering this hormone to the body directly could be an effective method to cause sunless tanning. What they found was that while it appeared to work, natural alpha-MSH had too short a half life in the body to be practical as a therapeutic drug. So they decided to find a more potent and stable alternative, one that would be more practical.

 

After synthesizing and screening hundreds of molecules, the researchers headed by Dr. Victor Hruby, found a peptide that after trials and testing seemed to not only be safe but also approximately 1,000 times more potent than natural α-MSH. They dubbed this new peptide Melanotan. Since their discovery, numerous studies dating back to the mid-1980s have shown no obvious toxic effects of Melanotan. Because skin cancer (melanoma) today is a major health concern, Melanotan is expected to be used as a drug to combat it. Melanotan will do this by stimulating the body's natural tanning mechanism to create a tan without first needing exposure to harmful levels of UV radiation. This in turn will reduce the potential for skin damage that can eventually lead to skin cancer.

 

 

 

The Development of Melanotan 1


The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result.


Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan-1, which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).

 

 

 

Application


Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP).


A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

 

99% Purity with Competitive Price Injectable Melanotan I CAS 75921-69-6 for Bodybuilding and Skin Color Change 1

 

Applications:

Like every peptide we have discussed thus far, please remember that peptides come in the form of a white delicate powder and should be stored out of light in a cool dry place. All peptides need to be reconstituted with bacteriostatic water or sodium chloride specifically used for injections. In order to use Melanotan II effectively, you need to understand your skin type. To keep things simple, we can go ahead and break skin types into three categories.

Skin Type 1: Very fair skin, never tans. Dosages: 50-60mgs or 5-6vials.
Skin Type 2: Fair skin, burns but sometimes tans. Dosages: 30-40mgs or 3-4 vials.
Skin Type 3: Medium skin, sometimes burns and always tans. Dosages: 20mgs or 2 vials.
Beyond that, if your pigmentation is already naturally olive or darker, you will need to use less Meanotan II for your tanning needs. The tan results coupled with exposure to sunlight and UV rays should last a user all summer or through a season.

 

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99% Purity with Competitive Price Injectable Melanotan I CAS 75921-69-6 for Bodybuilding and Skin Color Change 4

Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com

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