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Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number Yk11
Minimum Order Quantity 10g
Price US $20-$23
Packaging Details Aluminum foil bag packing.Or other custom packaging.
Delivery Time 1-3 working days to ship, then about 5-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Payment Method
Supply Ability 50KG per Month
Product Details
Prouduct Names GW0742 Purity 99% Min
Grade Standard Medical Grade Cas No. 317318-84-6
Shelf Life 2-3 Years Assay HPLC 99%
Color White Powder Specification 10g,50g,100g,1kg Per Bag
High Light

Andarine GTX-007 SARMs Steroids Powder

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HPLC 99 SARMS Raw Powder

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Product Description

Powder GW-0742 / GW 0742 Selective Androgen Receptor Modulators Muscle Building CAS 1196133-39-7

Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 0

Product Name GW 0742
Alias GW 610742, GW-0742
CAS 317318-84-6
MF C21H17F4NO3S2
Purity 99.50%
Dosage 20-30mg per day
Grade Pharmaceutical Grade
Appearance White powder
Brand Name DW
Standard USP
Stock Mass Stock
Packing Methods designed disguised packing ways, 100% pass custom guarantee
Delivery time within 18 hours after payment confirmed
Payment T/T, , , Bitcoin
Usage GW 0742 had been investigated as a potential treatment for obesity,diabetes,dyslipidemia and cardiovascular disease .

 

Description:

 

GW0742 is a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice.


A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator 2. These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The peroxisome proliferator-activated receptor δ (PPARδ) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 µM. The highest antagonist activity for GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742 behaved as PPAR agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations. A unique spectroscopic property of GW0742 was identified as well. In the presence of rhodamine-derived molecules, GW0742+ increased fluorescence intensity and fluorescence polarization at an excitation wavelength of 595 nm and emission wavelength of 615 nm in a dose dependent manner. The GW0742-inhibited NR-coactivator binding resulted in a reduced expression of five different NR target genes in LNCaP cells in the presence of agonist. Especially VDR target genes CYP24A1, IGFBP-3 and TRPV6 were negatively regulated by GW0742. GW0742 is the first VDR ligand inhibitor lacking the secosteroid structure of VDR ligand antagonists. Nevertheless, the VDR-meditated downstream process of cell differentiation was antagonized by GW0742 in HL-60 cells that were pretreated with the endogenous VDR agonist 1,25-dihydroxyvitamin D3.

 

Application:

GW 0742 activates AMP activated protein kinase and stimulates glucose uptake in skeletal muscle tissue , and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with prediabetic metabolic syndrome , most likely by stimulating fatty acid oxidation . GW0742 has been proposed as a potential treatment for obesity and related conditions , especially when used in conjunction with a synergistic compound AICAR , as the combination has been shown to significantly increase exercise endurance in human.

 

 

 
Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com

 

SARMS product list
Product Cas No Product Cas No
MK-2866 (Ostarine; Enobosarm; GTX-024; S-1) 1202044-20-9 841205-47-8 MK-677 (MK-0677; Ibutamoren; Ibutamoren; nutrobal; L 163,191; Ibutamoren mesylate; Crescendo) 159752-10-0
GW501516 (Cardarine) (GSK-516) GW1516 317318-70-0 YK11 (YK-11-OA) 431579-34-9
GW0742   S4 (Andarine; GTX-007; Acetamidoxolutamide) 401900-40-1
LGD-4033 (Ligandrol) 1165910-22-4 S23 1010396-29-8
RAD-140 (Testolone) 118237-47-0 SR9009 (Stenabolic) 1379686-30-2
SR9011 1379686-29-9 Another products: Peptide,HGH,steroids....
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Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 1
 
1. We offer RESHIP service with free cost if goods were catched by custom.

 

2.Full experience of large numbers containers loading in Chinese sea port.


3. We provide more customized services:Products, Labels, Boxes.....


4. payment term:,, Bank Transfer and BTC or Another Payment Method.

Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa

 

Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com

 

Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa

 

Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 2Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 3

 

Telegram/Whatsapp/Skype:008613798562250

 

Email:manager@szmallbio.com

Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 4Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 5Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 6Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7 7

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Email:manager@szmallbio.com
 
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