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Light yellow Powder Raloxifene Hydrochloride / Raloxifene HCl For Anti Estrogen

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number 82640-04-8
Minimum Order Quantity 10g
Price negotiable
Packaging Details 10g,50g,1kg bag
Delivery Time 1-3 working days to ship, then about 5-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Payment Method
Supply Ability 1000 kg per month
Product Details
Name Raloxifene Hydrochloride MOQ 10G
Package Foil Bag,drum Appearance Light Yellow Powder
Cas No. 82640-04-8 Shelf Life 2 Years
MF C28H28ClNO4S Assay HPLC 99%
High Light

99 Purity Pharmaceutical Raw Materials

,

Anastrozole Pharmaceutical Raw Materials

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Product Description

Raloxifene Hydrochloride powder CAS 82640-04-8 Raloxifene HCL for Anti Estrogen

 

Light yellow Powder Raloxifene Hydrochloride / Raloxifene HCl For Anti Estrogen 0

Raloxifene Hydrochloride

 

CAS:82640-04-8

MF:C28H28ClNO4S

MW:510.04

Synonyms:RALOXIFENE HCL;RALOXIFENE HYDROCHLORIDE;ly156758 ;methanone,(6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidin ;KEOXIFENE;KEOXIFENE HYDROCHLORIDE;LY 139481;AKOS 92138

 
 

Properties

 

Melting point:250-253°C

storage temp. -20°C Freezer

solubility DMSO: 28 mg/mL, soluble

 

 

Abstract

 

Raloxifene hydrochloride is a second-generation Selective Estrogen Receptor Modulator (SERM) of the benzothiophene family. This drug is similar in effect to tamoxifen, exhibiting estrogen receptor antagonist (blocking) properties in some tissues while acting as an estrogen receptor agonist (activator) in others.

The main point of variation between these two agents is their tissue selectivity. While raloxifene hydrochloride is a strong anti-estrogen in breast and uterine tissues, it appears to be estrogenic in bone. This allows it to protect bone density, mimicking the beneficial effects of endogenous estradiol. This is quite different from tamoxifen, which is anti-estrogenic in both breast and bone.

In a role that was novel for an anti-estrogen, raloxifene hydrochloride was approved by the FDA for the prevention and treatment of osteoporosis in post-menopausal women. It is also being investigated for several other potential uses, including the treatment and prevention of cardiovascular disease, breast cancer, gynecomastia, prostate cancer, acromegaly, and uterine cancer.


Raloxifene Hydrochloride is used to help prevent and treat thinning of the bones (osteoporosis) only in postmenopausal women.

It works like an estrogen to stop the bone loss that can develop in women after menopause, but it does not increase the bone density as much as daily 0.625 mg doses of conjugated estrogens. Raloxifene Hydrochloride will not treat hot flashes of menopause and may cause hot flashes to occur. Also, Raloxifene Hydrochloride does not stimulate the breast or uterus as estrogen does.

Raloxifene Hydrochloride lowers the blood concentrations of total and low-density lipoprotein (LDL) cholesterol, the bad cholesterols, but it does not increase concentrations of high-density lipoprotein (HDL) cholesterol, the good cholesterol, in your blood.

Raloxifene Hydrochloride is also used to lower chances of having invasive breast cancer in postmenopausal women with osteoporosis or at high risk of having invasive breast cancer .
This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Raloxifene Hydrochloride is used in certain patients with the following medical conditions:

Breast cancer prevention in high-risk women who have already gone through menopause.

Light yellow Powder Raloxifene Hydrochloride / Raloxifene HCl For Anti Estrogen 1

 

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2.Full experience of large numbers containers loading in Chinese sea port.


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