2627 69 2 Peptide Steroid Hormones 50mg Aicar Powder

Factory Supply aicar peptide Top quality peptide best price 50mg aicar powder

Product Name: Aicar

CAS No: 2627-69-2

Molecular Formular: C9H14N4O5

Molecular Weight: 258.2

Appearance: Off-white powder

Chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide
Specification: 50mg/vial, 10vial/box
Appearance: White Lyophilized Powder
Place of Origin: China

AICAR (AICA-Riboside) strongly inhibits the transcription of PPARα and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).

application:

(1) Aicar Applied in phamaceutical field, it is used as phamaceutical raw material to treat injuries from fall, infectious hepatitis and epidemic cerebrospinal meningitis.
(2) Aicar Applied in healthcare field, it is used in the health products to nourish brain, protect liver and improve sleep quality.
(3) Aicar Applied in comestics, it is used to promote skin metabolism and make skin more tender and firm.

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