Fat Burning / Anti - Aging 5mg Hexarelin Peptide CAS 140703-51-1

Detailed Description:

Hexarelin is another hexapeptide like GHRP-6. Unlink the other GHRP’s out there, Hexarelin is the dark horse, the black sheep, the underdog not usually mentioned and often over looked for certain qualities. This grossly underestimated peptide shouldn’t be pushed to the side, but rather examined to understand its benefits and usability for bodybuilders and athletes alike.

For starters Hexarelin is not your average GHRP. The structure of the amino acid is that of a hexapeptide known to help promote the release of growth hormone (GH). The mechanism of action is not yet fully understood by scientists. However, what we know is that hexarelin has the ability to act both on the pituitary gland and the hypothalamus. It is known to give the largest release of GH than any other GHRP.

Benefit:

Interestingly, the most amazing finding with hexarelin was its ability to act on cardiac receptors separate from the GH releasing properties. The peptide can directly aid in cardio protective left ventricular pressure issues, as well as, help healing scar tissue on the heart. Studies on lean and obese lab rats concluded that while lean rats were able to take advantage of the GH plasma increase better than the obese rats (the healthier the rat the more hexarelin effectively produced and utilized GH), obese rats did not see the same advantage. Separate from the studies that monitored GH, both lean and obese rats both received all of the cardio protective properties of hexarelin.

How does it work?

When Hexarelin is given as a subcutaneous injection, it activates the pituitary via a pulse, just like GHRP-6, and helps circulate growth hormone in the body. Unlike GHRP-6, it does not induce any hunger side effects. Hexarelin has the ability to not only raise the level of GH in the body but to also suppress somatostatin, which is the main culprit that inhibits GH from being released. This means that there will be more GH in abundance. In addition, hexarelin is the strongest GHRP available, so users should notice that desensitization can come much quicker than other GHRP’s. This makes it less ideal for long term use, but with hexarelin’s ability to raise healthy levels of IGF-1 and GH it can work perfect as a PCT tool for those coming off a synthetic GH/IGF-1 cycle. The potency of this peptide should not be underestimated and it comes with an increase in cortisol production as well as prolactin. Nothing close to what might be seen in elevated levels from steroid use, but compared to other GHRP’s it has the strongest affinity to raise cortisol/prolactin.

Applications:

The peak GH secretion rate following the first intravenous bolus of hexarelin was greater than that following the first bolus of GHRH-(1-29)-NH2 (P < 0.001), and was greatest following the administration of hexarelin with GHRH-(1-29)-NH2 (P < 0.001). The coadministration of the two secretagogues resulted in peak GH secretion rates significantly greater than the arithmetic sum of those following their isolated administration (P = 0.001), demonstrating synergism. Compared to saline, the administration of a second bolus of hexarelin, GHRH-(1-29)-NH2 or both resulted in significant further GH secretion (P = 0.02, P = 0.002, P = 0.03, respectively). The administration of a second bolus of hexarelin or hexarelin with GHRH-(1-29)-NH2 120 minutes after the first bolus resulted in lower peak GH secretion rates (P = 0.03). The reductions in peak GH secretion rates following the 60-minute boluses were not statistically significant. The peak GH secretion rates following the first GHRH-(1-29)-NH2 boluses were similar to those following the 60 and 120-minute GHRH-(1-29)-NH2 boluses (P = NS). Irrespective of the interval between the boluses of hexarelin with GHRH-(1-29)-NH2, the peak GH secretion rates following the second boluses were not significantly different from the arithmetic sum of those following the administration of the second boluses of hexarelin or GHRH-(1-29)-NH2, indicating loss of synergism on repeated administration.

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