White Powder Skin Protect CAS 75921-69-6 Melanotan II Peptide Steroid Hormones Bodybuilding Products

White Powder Skin Protect CAS 75921-69-6 Melanotan II Peptide Steroid Hormones Bodybuilding Products

Quick Details:

Product Name: Mt-1 Melanotan 1

CAS NO: 75921-69-6

Assay: 99%

Molecular Weight: 1646. 845

Density: 1. 5±0. 1 g/cm³

Molecular Formula: C₇₈H₁₁₁N₂₁O₁₉

Appearance: White Powder

Melanotan 1 Description:

1. MT-1 (or Melanotan I, or Afamelanotide, or CUV-1647) is a synthetic analog of peptides nature of endogenous melanocortine peptide alpha-melanocyte stimulating hormone. It has hormones nature as well as common proteins features, its molecular weight/mass is 1646. 88 and its molecular formula is C₇₈H₁₁₁N₂₁O₁₉.

2. Afamelanotide was specifically developed by American scientists LED by V. Hruby in 1991 as a possible research compound that can be used against skin cancer by stimulating tanning system which in own turn would generate protective natural tan during melanogenesis. So that synthetic analog was created to determine if it can show the same effect and stimulate melanocytes to produce and release melanin to protect skin from UV. Most of studies and trials were conducted in United States and Australia.

3. Developed research compound is quite stable cyclic form of original hormone but specifically has much longer half-life period. It works as agonist of specific melanocortin receptor and possesses such property as being selective; And thus it promotes increased level of eumelanin above usual pheomelanin, which provides higher efficacy of photoprotection abilities.

Function & Usage

1. Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

2. Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α -MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R, MC3-5R). As an analogue of α -MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.

Melanotan II COA:

A Potential Treatment For Skin Cancer:

It is known that the effects of α-MSH are mediated by melanocortin receptors.

MC1R is expressed in skin cells and has a high affinity for α-MSH and is the main receptor by which α-MSH signals.

Based on this fundamental information and observations of how α-MSH impacts melanomic cells, one study has hypothesized that "α-MSH acts initially to reduce initial tumor spread, but paradoxically protects those cells that escape from the primary tumor.

As an analog of α-MSH, it is logical to believe that Melanotan II may have similar effects.

Treatment For Male And Female Sexual Dysfunction:

Melanotan-1, the precusor to Melanotan II, would eventually be licensed for commercialization as a tanning agent and has been in development for use as a potential "therapeutic tan," with minimal need for prolonged sun exposure. In the initial clinical testing of Melanotan II, an immediate and unexpected response was noted. The main subject experienced an erection shortly after administration. It was suggested that Melanotan II "may prove equally effective in women" as a "treatment of female sexual dysfunction. At least one study has observed that administration of Melanotan II may increase sexual desire, which should warrant further "investigation of centrally acting agents on disorders of sexual desire.

Theoretically, Melanotan II may enhance sexual function in males (erectile activity) and females (increased levels of sexual desire and genital arousal). Unlike other sexual-enhancement drugs, it is hypothesizedd that Melanotan II works at a neurological level, eliciting a more "natural" sexual response with minimal side effects. It was suggested that Melanotan II "may prove equally effective in women" as a "treatment of female sexual dysfunction. [5] At least one study has observed that administration of Melanotan II may increase sexual desire, which should warrant further "investigation of centrally acting agents on disorders of sexual desire.

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