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CAS 33515-09-2 Gonadorelin Peptides Steroids Pre-Reconstituted Gonadorelin Freeze Dried Peptide For Adult
Place of Origin | China |
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Brand Name | ML |
Certification | TESTING |
Model Number | 33515-09-2 |
Minimum Order Quantity | 1 box |
Price | US $28.5-$31.5 |
Packaging Details | 2mg per vial 10 vails/box, white box packaging and any method of packing applicable to the product.For safe delivery. |
Delivery Time | 1-3 working days to ship, about 3-12 working days for delivery |
Payment Terms | , , T/T, Bank transfer and BTC or Another Reliable Payment Method |
Supply Ability | 5000 boxes per month |
Product Name | Gonadorelin | Purity | 99%min |
---|---|---|---|
CAS | 33515-09-2 | Grade Standard | Medicine Grade |
Shelf Life | 2 Years | Assay | HPLC 99% |
Color | White Powder | Storage | Cold Storage |
High Light | HPLC 99 Weight Loss Peptides,5000iu/ Vial Human Growth Hormone Supplement |
CAS 33515-09-2 Gonadorelin Peptides Steroids Pre-Reconstituted Gonadorelin Freeze Dried Peptide For Adult
Gonadorelin CAS: 33515-09-2
Sequence: P-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Gonadorelin MF: C55-H75-N17-O13
Gonadorelin MW: 1182
Gonadorelin Purity: 99%
Gonadorelin Specification: 2mg/vial, 10mg/vial
Appearance: White Lyophilized Powder
Place of Origin: China
Gonadorelin Standard: USP
Gonadorelin Certification: SGS
Method of Analysis: HPLC
Gonadorelin Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
Description:
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.
GnRH is available as gonadorelin hydrochloride )and gonadorelin diacetate tetrahydrate for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
Administration of gonadorelin is used to simulate the physiologic release of GnRH from the hypothalamus in treatment of delayed puberty, treatment of infertility caused by hypogonadotropic hypogonadism, and induction of ovulation in those women with hypothalamic amenorrhea. This results in increased levels of pituitary gonadotropins LH and FSH, which subsequently stimulate the gonads to produce reproductive steroids.
GnRH is available as gonadorelin hydrochloride(Factrel®)and gonadorelin diacetate tetrahydrate(Cystorelin®)for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.
Gonadorelin is used by women who are missing menstrual periods due to low levels of gonadotropin-releasing hormone (GnRH). It may be used as part of female infertility treatment. This medication provides GnRH that the body needs for the growth and release of mature eggs from the ovaries (ovulation).
Systemic - Like naturally occurring releasing hormone (GnRH), gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response. For the treatment of amenorrhea, delayed puberty, and infertility the administration of gonadorelin is used to simulate the physiologic release of GnRH from the hypothalamus in treatment of delayed puberty, treatment of infertility caused by hypogonadotropic hypogonadism, and induction of ovulation in those women with hypothalamic amenorrhea. This results in increased levels of pituitary LH and FSH, which subsequently stimulate the gonads to produce reproductive steroids.
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