HPLC Hexarelin Muscle Building Peptides Most Effective 98 Percent Purity

Detailed Description:

Hexarelin Indications: Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the grow factor family which stimulates the release of grow hormone (GH). It can be used medically to treat GH deficiency. Hexarelin is a good all purpose anabolic. Also, since we know that IGF and GH use produces a shutdown of your endogenous levels of those hormones, Hexarelin also seems very useful for "GH-PCT" or "IGF-PCT", as it can help restore your natural levels of those hormones after a cycle of them.

Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of growth hormone by the pituitary gland. The pathway activated by binding of ghrelin to the growth hormone secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems. One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.

Benefits:

Interestingly, the most amazing finding with hexarelin was its ability to act on cardiac receptors

separate from the GH releasing properties. The peptide can directly aid in cardio protective left

ventricular pressure issues, as well as, help healing scar tissue on the heart. Studies on lean and

obese lab rats concluded that while lean rats were able to take advantage of the GH plasma

increase better than the obese rats (the healthier the rat the more hexarelin effectively produced

and utilized GH), obese rats did not see the same advantage. Separate from the studies that

monitored GH, both lean and obese rats both received all of the cardio protective properties of

hexarelin.

The functionality:

Hexarelin (Hexarelin Acetate) is chemically designed as L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-

L-tryptophyl-D-phenylalanyl-L-lysinamide. Hexarelin (Hexarelin Acetate) is a potent GHRP-6

analog, whose structure (His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2) creates a greater stability

than GHRP-6 due to a substituted (2 Me)Trp. Hexarelin has a half-life of about 70 min, longer than

that of GHRP-6. Replacement of the naturally occurring L-amino acids for the D-configuration

results in these longer half-lives.

Secretion:

Hexarelin has shown that it is highly stimulated at 30 minutes after being induced by rapid and

sustained GH secretion. The pituitary gland produces GH in the brain, in children this hormone

helps them to grow and in adults it helps to maintain muscle and burn fat. In one sixteen-week

study, it has been shown that GH levels return to normal after stopping use after four weeks.

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