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Pentadecapeptide Bpc 157 Peptide for Healing and Production of Collagen
| Place of Origin | China |
|---|---|
| Brand Name | ML |
| Certification | TESTING |
| Model Number | 137525-51-0 |
| Minimum Order Quantity | 1 box |
| Price | US $40-$80 |
| Packaging Details | White box, Carton packaging Or custom packaging. |
| Delivery Time | 1-3 working days to ship, then about 5-12 working days for delivery |
| Payment Terms | , , T/T, Bank transfer and BTC or Another Payment Method |
| Supply Ability | 5000 boxes per month |
Product Details
| Other Names | Pentadecapeptide | Purity | 99% Min |
|---|---|---|---|
| Grade Standard | Medical Grad | Cas No. | 137525-51-0 |
| Shelf Life | 2 Years | Assay | HPLC 99% |
| Color | White Freeze-dried Powder | Type | Auxiliaries And Other Medicinal Chemicals |
| High Light | HPLC 99 Weight Loss Peptides,5000iu/ Vial Human Growth Hormone Supplement |
||
Product Description
Pentadecapeptide Bpc 157 Peptide for Healing and Production of Collagen
| CAS | 137525-51-0 |
|---|---|
| Synonyms | Booly protection compound 15, Pentadecapeptide, |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Concrention | 2mg/vial 5mg/vial,10mg/vial |
| M.F | C62H98N16O22 |
| M.W | 1419.53552 |
| PURITY | ≥99% (HPLC) |
| Physical State | Lyophilized Powder |
| Solubility | Soluble in water or 1% acetic acid |
| Storage | Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C. |
BPC 157 is a pentadecapeptide, meaning that is comprised of a chain of 15 amino acids. It has been determined to be a partial sequence of body protection compound (BPC) that can be isolated from gastric juices located in animal test subjects. It possesses a molecular mass of 1419.53552, and its molecular formula is C62H98N16O22. It can be referred to by the alternate names BPC 15, BPC-157, or Booly Protection Compound 15.
Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H(2)O(2) stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway.
BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, it significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle.
Used In Humans :
well BPC 157 is known for super quick and professional Joint/tendon/ligament healing in all phases of clinical trials. Studies are shown here: BPC 157 has been shown in studies to heal torn quadriceps muscles, detached achilles tendon, muscles that have been damaged/crushed. Demonstrating dramatic fast recovery from muscle tears. Tendon to bone healing - increased ligament healing, BPC 157 has a variety of protective effects in the organs. Clinical trials demonstrate healing and prevention of stomach ulcers and it is being studied as a burn treatment. Trials show it may help repair some liver damage after prolonged chronic alcohol exposure. No adverse reactions have been seen in clinical trials.
BPC 157 peptide has been shown to heal a variety of wounds in all areas researched, including internal organs, muscles, ligaments, tendons, skin, internal lacerations from surgery. It can have a use in the medical industry help heal and get rid of stomach ulcers caused by people abusing NSAID drugs.
Bpc 157 Application
BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, it significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle.
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