-
Peptide Steroid Hormones
-
Peptide Growth Hormone
-
Bodybuilding Human Growth Hormone
-
Testosterone Anabolic Steroid
-
SARMS Raw Powder
-
Trenbolone Steroid Powder
-
Primobolan Masteron Raw Steroids
-
Liquid Anabolic Steroid
-
Pharmaceutical Raw Materials
-
Male Enhancement Steroids
-
Weight Loss Steroids
-
CBD Isolate Powder
-
Pharmaceutical Adjuvants
-
Chris karps,SwedenAlways pleasure to work with you Wendy! Good communication, service minded and top notch products .
-
Andy Marchant,United Kingdomvery happy and tell you every step of the way posted when arrived and when due for delivery the quality is excellent
-
shane bassette,United StatesThis company is one worth buying from I have purchased several times from them and will continue buying in the future , Excellent customer service Very helpful with my order I would give them 10 stars if I could Thanks again
Cas 317318-84-6 Powder Gw-0742 / Gw 0742 Selective Androgen Receptor Modulators Muscle Building Cas 1196133-39-7
Place of Origin | China |
---|---|
Brand Name | MALL |
Certification | TESTING |
Model Number | Yk11 |
Minimum Order Quantity | 10g |
Price | US $20-$23 |
Packaging Details | Aluminum foil bag packing.Or other custom packaging. |
Delivery Time | 1-3 working days to ship, then about 5-12 working days for delivery |
Payment Terms | , , T/T, Bank transfer and BTC or Another Payment Method |
Supply Ability | 50KG per Month |
Prouduct Names | GW0742 | Purity | 99% Min |
---|---|---|---|
Grade Standard | Medical Grade | Cas No. | 317318-84-6 |
Shelf Life | 2-3 Years | Assay | HPLC 99% |
Color | White Powder | Specification | 10g,50g,100g,1kg Per Bag |
High Light | Andarine GTX-007 SARMs Steroids Powder,HPLC 99 SARMS Raw Powder |
Powder GW-0742 / GW 0742 Selective Androgen Receptor Modulators Muscle Building CAS 1196133-39-7
Product Name | GW 0742 |
Alias | GW 610742, GW-0742 |
CAS | 317318-84-6 |
MF | C21H17F4NO3S2 |
Purity | 99.50% |
Dosage | 20-30mg per day |
Grade | Pharmaceutical Grade |
Appearance | White powder |
Brand Name | DW |
Standard | USP |
Stock | Mass Stock |
Packing Methods | designed disguised packing ways, 100% pass custom guarantee |
Delivery time | within 18 hours after payment confirmed |
Payment | T/T, , , Bitcoin |
Usage | GW 0742 had been investigated as a potential treatment for obesity,diabetes,dyslipidemia and cardiovascular disease . |
Description:
GW0742 is a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice.
A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator 2. These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The peroxisome proliferator-activated receptor δ (PPARδ) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 µM. The highest antagonist activity for GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742 behaved as PPAR agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations. A unique spectroscopic property of GW0742 was identified as well. In the presence of rhodamine-derived molecules, GW0742+ increased fluorescence intensity and fluorescence polarization at an excitation wavelength of 595 nm and emission wavelength of 615 nm in a dose dependent manner. The GW0742-inhibited NR-coactivator binding resulted in a reduced expression of five different NR target genes in LNCaP cells in the presence of agonist. Especially VDR target genes CYP24A1, IGFBP-3 and TRPV6 were negatively regulated by GW0742. GW0742 is the first VDR ligand inhibitor lacking the secosteroid structure of VDR ligand antagonists. Nevertheless, the VDR-meditated downstream process of cell differentiation was antagonized by GW0742 in HL-60 cells that were pretreated with the endogenous VDR agonist 1,25-dihydroxyvitamin D3.
Application:
GW 0742 activates AMP activated protein kinase and stimulates glucose uptake in skeletal muscle tissue , and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with prediabetic metabolic syndrome , most likely by stimulating fatty acid oxidation . GW0742 has been proposed as a potential treatment for obesity and related conditions , especially when used in conjunction with a synergistic compound AICAR , as the combination has been shown to significantly increase exercise endurance in human.
SARMS product list | |||
Product | Cas No | Product | Cas No |
MK-2866 (Ostarine; Enobosarm; GTX-024; S-1) | 1202044-20-9 841205-47-8 | MK-677 (MK-0677; Ibutamoren; Ibutamoren; nutrobal; L 163,191; Ibutamoren mesylate; Crescendo) | 159752-10-0 |
GW501516 (Cardarine) (GSK-516) GW1516 | 317318-70-0 | YK11 (YK-11-OA) | 431579-34-9 |
GW0742 | S4 (Andarine; GTX-007; Acetamidoxolutamide) | 401900-40-1 | |
LGD-4033 (Ligandrol) | 1165910-22-4 | S23 | 1010396-29-8 |
RAD-140 (Testolone) | 118237-47-0 | SR9009 (Stenabolic) | 1379686-30-2 |
SR9011 | 1379686-29-9 | Another products: Peptide,HGH,steroids.... |

2.Full experience of large numbers containers loading in Chinese sea port.
3. We provide more customized services:Products, Labels, Boxes.....
4. payment term:,, Bank Transfer and BTC or Another Payment Method.
Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa
Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa
Contact US