Raw Mechano Growth Factor MGF 2mg Bodybuilding Supplements for muscle growth

Raw Mechano Growth Factor MGF 2mg Bodybuilding Supplements for muscle growth

Quick Detail:

Unit Size :2 mg/vial
Unit Quantity :1 Vial
Synonyms :MGF (Mechano Growth Factor)
Molecular Formula :C121H200N42O39
Molecular Weight :2867.14
Sequence :H-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-

Glu-Glu-His-Lys-NH2
Appearance :White Powder
Purity :99.17%
Identity (ESI-MS) :2867.14±3.7
Source :Chemical Synthesis
Storage :Lyophilized MGF is stable at room temperature for 90 days,however it should be stored in a

freezer below -8C for any extended period of time. After reconstituting MGF should be refrigerated at

temperatures not to exceed 36 F.

2. Description:

Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue, Its called MGF as IGF-1Ec is a bit of a mouthful and harder to identify amongst the other igf variants.
What makes MGF special is its unique role in muscle growth.
MGF has the ability to cause wasted tissue to grow and improve itself by activating muscle stem cells and increasing the upregulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth.

MGF (mechano growth factor) has been used by bodybuilders and athletes for a few years already.After resistance exercise ,IGF-1 is released within the muscle. Specifically, at this time, immediately following the mechanical use of a muscle, the IGF-I gene is spliced towards MGF which initiates hypertrophy and repair of local muscle damage. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. (1) It differs from “regular” IGF-1

mainly due to it’s C-Terminal sequence.

MGF Peptide is a much commonly used abbreviation for "Mechano Grow Factor" peptide which is a very popular exercise supplement used by body builders & athletes. The biomolecule was first discovered & documented by a well known biochemist called Goldspink. It is also known as "I-G-F-1EC"and is derived from damaged or worn out tissue. The peptide molecule is known to initiate repair of damaged tissues or local muscles and is released into the body after extensive training, resistance exercise etc. However, one should note that the peptide is chemically different from commonly found "I-GF-1" due to the existence of a C Terminal Sequence.

3. Applications:

It was first discovered in the muscle by Goldspink, et al. In human muscle, a 49-base insert changes the reading frame in mechano growth factor (MGF) as compared to IGF-1.

When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis. After

this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.

MGF (mechano growth factor) has been used by bodybuilders and athletes for a few years already. After resistance exercise ,IGF-1 is released within the muscle. Specifically, at this time, immediately following the mechanical use of a muscle, the IGF-I gene is spliced towards MGF which initiates hypertrophy and repair of local muscle damage. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. (1) It differs from "regular" IGF-1 mainly due to it's C-Terminal sequenc.
MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-Ireceptor domain which ithen in turn ncreases protein synthesis turnover, and therefore can if used correctly improve muscle mass over time.

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