PEG-MGF Peptide Steroid Hormones Mechano Growth Factor for Muscle

Hot sell Peg Mgf Peptide Powder PEG-MGF 2mg/Vial Bodybuilding

PEG-MGF Quick details:

Product name: PEG MGF; Pegylation of Mechano
Sequence: PEG-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-NH2
Molecular formula: C121H200N42O39
Molar Mass: 2867.2
Purity: ≥99% (HPLC)
Physical State: Lyophilized Powder
Synonyms: Pegylated MGF, PEG Ec
PEG MGF (Pegylated)
Usage: PEG-MGF (Pegylated Mechano ) is one of my personal favorite peptides. In fact, it's the best variant on the market today when it comes to site growth. Specifically, it's a IGF-1Ec splice that's responsible for both damaged muscle recovery and satellite cell growth.
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PEG MGF Profile:

PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down. Neurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.

Why do you choose PEG MGF?

Base MGF which is produced in liver and secreted into the blood stream, only lasts for about 5-7 minutes before it breaks down. This is the regular "base" MGF version that's not widely used due to the short half-life. Just as IGF-1 was modified to be IGF-1LR3 (the longer acting version), the same has been done with MGF. The additive polyethylene glycol was added to the MGF chain in order to give it a half life of several days!
If you have been training with weights, then you have already been using your own MGF that your body creates. IGF-1 is spliced due to its response to broken down muscle tissue and one of the splices produced is IGF-1Ec, better known as mechano growth factor. Basically, MGF is a version of IGF, specifically IGF-1Ec. MGF is an amazing variant that directly helps with the up-regulation of protein synthesis and nitrogen retention. This is why I think that PEG MGF is the best variant of the IGF-1 series. After you have broken down muscle tissue (post training), you can use the peptide PEG MGF and reap the benefit of its response to damaged muscle tissue. In addition, it will help you signal growth in nearby undamaged muscled cells. This gives it the unique ability to grow lagging body parts in areas where muscle growth is desired.

PEG-MGF Usage:

It will circulate your body binding to the receptors where muscle tissue damage has taken place. Administration should be timed post workout or on recovery days when you plan on resting. Since mechano growth factor is a variant of IGF-1, you do not want to use MGF pre-workout because it will have to fight for position with IGF-1 as they both try to bind to the same receptor. IGF-1 has a much stronger affinity to bind then MGF.An insulin syringe needs to be used to inject subcutaneously or intramuscularly with a dose around 200-400mcg. Bilateral dosing can be used, but a single site administration will work just as well.

PEG-MGF Applications:

PEG-MGF, or PEGylated Mechano Grow Factor is a new and innovative form of MGF that outperforms natural MGF many times over. MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes.

PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule(in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down.

MGF exhibits local effects in skeletal muscle and without cannot travel through the body without modification. The problem with synthetic MGF is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, MGF only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream. It is also short acting so stability is not an issue. By PEGylating the MGF it is almost as efficient as local produced MGF when used intramuscularly. This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule.

The polyethylene glycol groups protect the peptide but don't surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein. TNeurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.

Why Mechano Grow Factor? Resistance training or more specifically, a training that causes our muscles to work beyond their usual power leads to that familiar 'burning' sensation we all have had a chance to experience during an exercise. What happens to our muscles at that point is the following:

Every muscle is a cluster of muscle fibers (muscle cells), which at the point of extreme efforts tend to tear. The tearing of the muscle fibers is what causes the burning sensation. The torn parts form certain 'cavities' in the muscle tissue and those cavities represent a chance for a muscle to grow. After those 'cavities' are filled up with the muscle 'matter', we are left with a muscle of an increased mass.

Why 'Mechano'? Because tearing of the muscle fibers is an actual mechanical damage, and the only way to achieve that kind of damage is through mechanical stimulation of the muscle tissue. Why 'Grow Factor'? Because Mechano Grow Factor is responsible for accelerated muscle build-up processes. Besides accelerating muscle build-up processes Mechano Grow Factor also helps create new muscle cells. That's a simplified way of looking at the whole process. We will explain a few more details behind the workings of the Mechano Grow Factor and PEG-MGF shortly.

Mechano Grow Factor is a peptide hormone, a natural physiological byproduct created in a human body as a result of an exercise. Mechano Grow Factor (MGF) and IGF-1 (Insulin-like Grow Factor)are isoforms. Isoform is a protein with a slightly different form but usually a similarfunction as its 'fellow' isoform protein. Both, MGF (which is a liver derived hormone) and IGF-1 (which is produced in the muscles) have anabolic effects, but the anabolic powers of the MGF are greater than those of IGF-1. Anabolic quality of a substance is such that increases the levels of synthesis, either at a molecular or a cellular level, meaning the Mechano Grow Factor has a greater sensitivity to damages caused to muscles by exercise and induces the synthesis of a greater amount of proteins in skeletal muscles. Another favorable effect of the Mechano Grow Factor is its ability to activate the satellite cells of muscles (myosatellite cells). Myosatellite cells behave as stem cells. Once they are activated they fuse, form myoblastst, proceed to differentiate and form entirely new muscle cells. Again, the result is muscle growth.

But what about PEG-MGF? Why do we at BeFit4Free produce the PEGylated version of the Mechano Grow Factor if the MGF on its own has so much potential anyway?

PEGylated protein (PEG-MGF) is the one that has Polyethylene Glycol added to it. The role of the Polyethylene Glycol molecule is to preserve the integrity of the Mechano Grow Factor. Unlike the naturally produced Mechano Grow Factor, the injected MGF needs to enter the circulatory system. That is where the problem for the MGF arises. MGF is not stable in such environment and in order to be able to reach its final destination and fulfill its role it needs to be PEGylated (and turned into PEG-MGF). Polyethylene Glycol serves as a kind of a shell protecting the MGF from reacting to its surroundings before it reaches its final destination. It makes the PEG-MGF much more stable and long-lasting than Machano Grow Factor could be on its own.

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