||Epitalon;Epithalon;Glycine, L-alanyl-L-a-glutamyl-L-a-aspartyl-;L-alanyl-L-alpha-glutamyl-L-alpha-aspartylglycine;9: PN: WO02090380 PAGE: 55 claimed protein; Synonyms: Epithalon, LS-72251, AR-1J2975, AC1L55Y7, AC1Q5OK4
||Epitalon comes as lyophilized powder. It is recommended to inject 1 - 2ml of sterile or bacteriostatic water into the vial and mix gently, the solution should be kept refrigerated between 2 - 8 degrees Celsius for maximum 20 days.
Epithalamin was first discovered in the late 1980's by Prof. Vladimir Khavinson from St. Petersburg, Russia. It has been studied extensively ever since. It is known by several names, including Epitalon, Epithalon, Epithalone, Epithalamin and Epithalamine. Since all the patents are held by the Russian inventor there is not much interest for this tetra-peptide from the western big pharma industry. This makes the substance fairly unknown in the west due to the absence of marketing usually seen with big pharma products. In Russia it is currently in clinical studies and shows prospective results as treatment for liver disorders, neuropathology, psychiatry and geriatrics.
Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in humans. This pineal peptide preparation is secreted in the epithlamium-epiphyseal region of the brain. Its more prominent tasks are: to regulate metabolism in the epiphysis, increase the sensitivity of hypothalamus to its natural hormonal influences, normalize the function of the anterior pituitary, regulate the levels of gonadotropins and melatonin in the body. Epithalamin increases a person's resistance to emotional stress and also acts as an antioxidant.
Epitalon (a.k.a. epithalon or epithalon) is a synthetically-derived tetrapeptide, meaning that it consists of four amino acid chains. It was discovered by the Russian scientist Professor Vladimir Khavinson, who then conducted epitalon-related research for the next 35 years in both animal and human clinical trials. The results were astounding. For the first time ever, human clinical trials proved beyond doubt that a substance consisted of powerful life extension and anti-aging properties.
Epitalons primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones.
Younger people produce a relatively large amount of telomerase and longer telomeres. The longer the telomere strands are, the better cell health and replication they provide. However, as people age, the production of telomerase falls and consequently cell replication and health decline. This is the main reason that people age.
Numerous studies have shown the importance of telomerase production and telomere rejuvenation in fighting the symptoms of aging. In one such study conducted on 913 pairs of twins, the twin with stronger telomerase production looked younger and had better health than his/her twin counterpart. In another study of 38 people who were 100 years or older, the healthiest participants had the strongest and longest telomeres.
As epitalon has been shown to increase the production of telomerase which in turn strengthens and lengthens telomeres, this means that epitalon can play a vital role in decreasing the aging process and thus extending human longevity.
This breakthrough discovery in understanding telomerase production shows that epitalon is the only known substance to increase telomerase production and telomere strand length, which are primary factors in fighting aging.
1. Epitalon decreases the age-related changes in immune and neuroendocrine systems, reduces the incidence of recurrent infections and chronic diseases.
2. Long term clinical trials have shown that in patients with age-related pathology Epithalamin eliminates imbalance in prooxidation and antioxidation systems.
3. Epithalon in patients with signs of accelerated aging showed normalizing effect on metabolism and condition of various functional systems. Elevated uric acid, alkaline phosphatase and cholesterol in elder patients returned to normal after 10 days of treatment, and remained stable in a several months peroid afterwards.
Epitalon decreases the age-related changes in immune and neuroendocrine systems, reduces the incidence of recurrent infections and chronic diseases. Long term clinical trials have shown that in patients with age-related pathology Epithalamin eliminates imbalance in prooxidation and antioxidation systems.Results of 12-months treatment with Epithalon in patients with signs of accelerated aging showed normalizing effect on metabolism and condition of various functional systems. Elevated uric acid, alkaline phosphatase and cholesterol in elder patients returned to normal after 10 days of treatment, and remained stable in a several months peroid afterwards.
According to scientific studies based on animal test subjects, Epithalon (also known as Epitalon) has been shown to function with telomeres, which are areas of repeating DNA sequences that function to prevent gene degradation near the end of chromosomes.
Over time, telomeres become too small and weak to contain the sequence because of cell division, and the DNA becomes disrupted, which signals the start of the aging process.Epithalon works to replenish the enzyme that allows telomeres to remain more stabilized and better equipped to hold DNA in place.
||10mg/vial, 10 vials/ kit
||White Lyophilized Powder
|Method of Analysis
||Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18ºC. Upon reconstitution of the peptide it should be stored at 4 ºCbetween 2-21 days and for future use below -18C.
||Tetrapeptide revealing geroprotective effect/ Anti Aging Epitalon is a protein peptide that can stimulate the body's own natural production of telomerase within our it's cells.By doing this, it strengthens telomeres for reproduction. Your body makes telomerase, but it needs to be stimulated with the right precursors.Over time it should lengthen the telomeres of cells and refresh your entire body.
As a result of epitalons effect on telomerase production, the benefits are unique and far-reaching. Benefits of epitalon include:
Increase of human lifespan
Significant boosting of energy levels
Promotion of deeper sleep
Delay and prevention of age-related diseases such as cancer, heart disease and dementia
Improvement of skin health and appearance
Healing of injured and deteriorating muscle cells
Delays or prevents age-related heart disease, cancer and dementia
Tumor prevention (inhibition of cancer cells due to protective effect of elongated telomeres)
Epitalon - Increasing human lifespan
The unique makeup of humans is determined by our DNA strands. On the tip of each DNA strand are telomeres, which prevent the loss of vital genetic information that happens each time a cell divides. Every time a cell divides, the telomeres get shorter. The more frequent the cell division, the shorter telomeres become, until they become too short, preventing further cell division, growth, and rejuvenation. Numerous studies have shown that the shortening of telomeres is linked to age-related diseases and is a good predictor of early death.
However, there is an enzyme produced naturally in our body called telomerase (not to be confused with 'telomeres') which reverses the process of telomere shortening and degradation. Unfortunately our telomerase production declines significantly as we age.
So, when telomerase production is reactivated, cells can exceed their time limit and continue to divide in a healthy manner, allowing us to live longer. This is exactly what epitalon does. It reactivates the production of telomerase which in turn strengthens and elongates the telomeres in our cell's DNA strands. This decreases cell death and degeneration, extending the lifespan of our cells and preventing a plethora of age-related diseases.
Early research into epitalon found that people who took epitalon had about a 25% longer life than their non-epitalon counterparts. These early studies triggered further studies which corroborated the initial findings. One of these studies reported that epitalon increased the lifespan of elderly and senile individuals by an incredible 50%.
Epitalon - Allowing a longer, healthier life
Through its stimulating action on telomerase production and the pineal gland, epitalon plays an important role in inhibiting cancerous tumor growth, increasing the effectiveness of deep sleep, preventing a wide variety of age-related diseases through its elimination of free radicals, and, most importantly, increasing human lifespan. In addition to all of this, it also promotes improved skin health and gives joint and muscle pain relief, the latter being a very common symptom of aging.
Epithalon dosage and course (cycle) duration:
Dosage depends on the purpose and severity of the damage which is treated. Epitalon can be used orally (less effective and large dose) or injected intramuscularly or under the skin (more effective at much smaller dose).
1. Oral Epithalon use (least effective):
duration: between 10 - 20 days
dosage: between 400 - 600 mg of Epithalon per day
daily frequency:200 mg per serving, between 2 - 3 servings per day (depending on the dosage)
2. Epithalon as nasal spray or drops (medium effectiveness):
duration: between 10 - 20 days
dosage: between 15 - 30 mg of Epithalon per day
daily frequency:total daily dosage split into 3 servings throughout the day
3. Injectable Epithalon use (most effective):
duration: 10 - 20 days
dosage: between 5 - 10 mg per day (20 mg intravenous for terminal patients)
frequency of injection:1 injection per day for low dose, 2 injections for higher dose (divided between morning and late afternoon injection)
Each 10 - 20 days course of Epithalamin is followed by 4-6 months pause before repeating the course again. Epitalon treatment can be repeated indefintely.