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Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth

Place of Origin China
Brand Name MALL
Certification TESTING
Model Number Follistatin 344
Minimum Order Quantity 1 box
Price US $270-$300
Packaging Details 1mg per vial 10 vails/box, white box packaging and any method of packing applicable to the product.For safe delivery.
Delivery Time 1-3 working days to ship, about 3-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Reliable Payment Method
Supply Ability 5000 boxes per month
Product Details
Purity 99% Min Grade Standard Medicine Grade
Product Name Follistatin 344 Shelf Life 2 Years
Type Auxiliaries And Other Medicinal Chemicals Assay HPLC 99%
Color White Powder Storage Cold Storage
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Product Description

Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth

Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 0

Quick details:

Appearance : White to off-white crystalline powder or lumps
Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
Water Content(Karl Fischer) : ≤5.0%
Acetate Content(by HPLC) : ≤15.0%
Amino Acid Composition : ±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N) : ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins : ≤5EU/mg
Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.

Description:

Follistatin 344 was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FST is a high-affinity activin binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Follistatin 344 quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene acts on similar pathways as FST regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting.

Does Follistatin Build Muscle?

In short, follistatin does build muscle but not necessarily in humans. A number of studies support the muscle-building and anti-degenerative effects follistatin in rodents. Unfortunately there is no formal research examining follistatin usage in human subjects but a quick Google search will yield countless amateur follistatin logs on bodybuilding and fitness forums.
When scientists bred a mouse producing no myostatin and extra follistatin it had 117% larger muscle fibers and 73% more total muscle fibers compared to the mice in the control group. [8] This study demonstrates that follistatin positively impacts muscle growth in ways beyond simply suppressing myostatin. Mice with suppressed myostatin had twice the muscle mass but mice with the follistatin transgene and suppressed myostatin had four times as much muscle mass compared to the control group.

Introduction of Follistatin :

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh).

Application:

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .

 

Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 1

 

 

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Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 2

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Human Growth Hormone Somatropin HGH 191aa Injections Buy Powder 191 aa hgh HGH Growth Hormone 191aa

 

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Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 3

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Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 4Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 5

 

Follistatin FST 344 Protein Peptide Hormones CAS 96827-07-5 For Muscle Growth 6

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