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China Best Supplier Sell 98% Freeze Dried Powder DSIP / Delta Sleep Inducing Peptide CAS:62568-57-4

Place of Origin China
Brand Name ML
Certification TESTING
Model Number Dsip
Minimum Order Quantity 1 box
Price US $25-$30
Packaging Details 2mg per vial 10 vails/box, white box packaging and any method of packing applicable to the product.For safe delivery.
Delivery Time 1-3 working days to ship, about 3-12 working days for delivery
Payment Terms , , T/T, Bank transfer and BTC or Another Reliable Payment Method
Supply Ability 5000 boxes per month
Product Details
Purity 99% Min Grade Standard Medicine Grade
Product Name Dsip Shelf Life 2 Years
Type Auxiliaries And Other Medicinal Chemicals Assay HPLC 99%
Color White Powder Storage Cold Storage
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Product Description

China Best Supplier Sell 98% Freeze Dried Powder DSIP / Delta Sleep Inducing Peptide CAS:62568-57-4

 

 

Product Details:

Alias: Delta Sleep Inducing Peptide
CAS: 62568-57-4
Sequence: TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU
MF: C35H48N10O15
MW: 848.813620
Purity: 99%
Specification: 2mg/vial
Appearance: White Lyophilized Powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.

 

Description

 

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:
N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α1 receptors in rats.It is unknown where DSIP is synthesized.

DSIP or Delta Sleep Inducing Peptide is a sML peptide used by neurons in the brain to communicate . There are many of these type peptides and they all influence the brain in certain ways.This particular peptide is found in several areas throughout the body and the exact mechanism by which it induces sleep is not exactly clear . It could be any one of a number of effects it exerts or a combination of many . It is present in the hpta, the brain, the melanocortin system , and various organs and tissues throughout the body .

DSIP,It increases the release of Hormone and decrease the release of Hormone Inhibiting Hormone . It also decreases corticotropin (aka stress hormone) . It is proven to improve SWS (slow wave sleep) and also impact the circadian rhythms working to reset your sleep clock if you will .With all the things this does in the body , and all the places it is found, the bottom line is it is proven to help you sleep . It is proven effective in research as a treatment for narcolepsy and normalizing sleep patterns .

 

Usage:

 

Delta sleep-inducing peptide (DSIP) , a nonapeptide with a unique amino-acid sequence (Table 1) , was isolated from the cerebral venous blood of rabbits subjected to low-frequency ('hypnogenic') electrical stimulation of the intralaminar thalamic nuclei (the so-called 'trophotropic zone '; Hess W. R. by Schoenenberger-Monnier group from Basel in 1977.

Delta ,In the following three decades , extensive studies carried out in a number of laboratories have demonstrated that DSIP , or some structurally closely related peptide(s) , is present in both free and bound forms in some cerebral structures , primarily the hypothalamus and limbic system , as well as pituitary and different peripheral organs , tissues and body fluids , where it co-localizes with several peptide and non-peptide mediators


DSIP (Delta Sleep-inducing Peptide) is a neuropeptide found in the hypothalamus, pituitary, and adrenal glands. Its isolation has allowed for extensive research which has found several possible primary and peripheral roles of this peptide. First, DSIP has been shown to induce sleep. Second, it may have benefits as an analgesic in treatment of chronic pain, sometimes as an adjunct treatment. Third, DSIP has been shown to block ACTH release and decrease levels of ACTH, stimulate LH release, and act as an inhibitor of the secretion of somatostatin. The source of production of DSIP is yet unknown; It may be produced in the central nervous system or in a peripheral organ. It is thought to pass through the blood-brain barrier (BBB) more easily than most known neuropeptides. As mentioned, DSIP has shown positive results in inducing slow-wave EEG (sleep). It has been shown to help treat narcolepsy and restore disturbed sleep patterns to normal sleep rhythms.

 

 

 

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1. We offer RESHIP service with free cost if goods were catched by custom.

 

2. Free Sample for you, Just pay shipping cost.

 

3.Full experience of large numbers containers loading in Chinese sea port.


4. We provide more customized services:Products, Labels, Boxes.....


5. payment term:,, Bank Transfer and BTC or Another Payment Method.

 

 
 
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